You may choose to focus exclusively on comparing, exclusively on contrasting, or on both-or your instructor may direct you to do one or both. First, pick useable subjects and list their characteristics. In fact, their individual characteristics determine whether the subjects are useable. After that, choose a parallel pattern of organization and effective transitions to set your paper above the merely average.
This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Topical agents can be unpleasant due to long-term therapies in patients with moderate to severe seborrheic dermatitis. Systemic antifungal therapy is another alternative in treatment. This study was conducted to compare the efficacy of oral fluconazole and terbinafine in the treatment of moderate to severe seborrheic dermatitis.
One study group took terbinafine mg daily and the other one fluconazole mg weekly for four weeks. Seborrheic dermatitis area severity index SDASI and the intensity of itching were calculated before, at the end of treatment, and two weeks after treatment.
Both drugs significantly reduced the severity of seborrheic dermatitis. Moreover, each index of SD severity reduced 0. The itching rate significantly diminished ; however, there was no difference between these two drugs statistically.
Both systemic antifungal therapies may reduce the severity index of SD. However, terbinafine showed more reduction in the intensity of the disease.
In other words, the more the primary intensity of the disease is, the more its reduction will be. This trial is resgistered with N1. Introduction Seborrheic dermatitis SD is a common chronic inflammatory skin disorder.
It is limited to specific areas of the skin such as the scalp, face, upper trunk, and flexures. It has also been found that there is a relation between overproduction of sebum and Malassezia yeast species, which exists naturally in the body [ 1 ].
There are different topical remedies to alleviate SD. Regarding disease progression and no response to topical therapy, patients should receive oral treatment. Alternatives are oral antifungal drugswith or without adjuvant therapies. It is the utmost to fulfill the best guideline for severe or persistent disease.
Terbinafine is a good choice to decrease severity of SD. However there are alternative drugs to this choice. Recently studies have shown that the fluconazole as a broad spectrum fungistatic drug can be used in treating seborrheic dermatitis.
Despite proof of the advantages of fluconazole and terbinafine in the treatment of seborrheic dermatitis, adequate and well-controlled studies concerning the comparison of oral fluconazole and terbinafine are scarce [ 2 — 8 ]. The objective of this study was to compare the efficacy of two antifungal medications in treating moderate to severe seborrheic dermatitis.
Study Population In this open randomized controlled parallel-group clinical study, 64 patients seeking treatment for moderate to severe seborrheic dermatitis in Department of Dermatology, Guilan University of Medical Sciences, Razi Hospital were enrolled.
Four patients discontinued the study and sixty patients 28 males and 32 females participated in this study. They were matched by age and sex in two groups. This study is launched in October to March and took three years and in order to eliminate seasonal impact, the study was conducted only in fall and winter.
Before recruitment, written informed consent was obtained.
Enrolled patients had no drug history of steroids, antifungal or other topical and systemic therapy for at least two weeks before entering the study washout time.
Subjects were excluded if they had any of the followings: The secondary endpoint of study was assessing the side effects of fluconazole and terbinafine. A sample size of 28 patients per group were determined. Treatment Computerized random allocation was applied with a 1: The drugs were sealed in numbered, opaque envelops according to the allocation sequence.
Allocation concealment was undertaken by an independent researcher.
Also, the processes of enrolling the participants and administering drugs were done by two residents of dermatology. None of them had any involvement in the trial. In one group 32 patientsfluconazole mg per week for four weeks was applied and in another group 32 patientsterbinafine mg per day received.
Four patients discontinued study and were lost to follow-up. Patients were evaluated four weeks after initiation of treatment and two weeks after treatment and scores were noted.
Laboratory tests regarding side effects were requested for all patients at each visiting time.Conclusions for the iPads: All Very Good to Excellent Top Tier Displays The primary goal of this Display Technology Shoot-Out article series has always been to publicize and promote display excellence so that consumers, journalists and even manufacturers are aware of and appreciate the very best in displays and display technology.
We point out which manufactures and display. Remember: Avoid simply telling us what something looks like--tell us how it tastes, smells, sounds, or feels!
Consider this Virginia rain smells different from a California drizzle. A mountain breeze feels different from a sea breeze.
We hear different things in one spot, depending on the time of day. If you are a school or college student unsure about what to write in your compare and contrast paper, find the list of great topics here.
Best Traditional Compare and Contrast Essay Topics for Students School and college students conduct in-depth research to enrich their compare and contrast essay drafts with important details.
FaceNet: A Uniﬁed Embedding for Face Recognition and Clustering Florian Schroff [email protected] Google Inc. Dmitry Kalenichenko [email protected] Research comes in all shapes and sizes. Sometimes a break from the usual can make class more exciting – for both student and teacher.
The librarians urge you to consider using library resources for something different. This essay will be words and will follow a comparison/contrast format.
Before you begin this research paper, be sure to read all of Chapter